Manufacturer: Alpha PharmaPack: 1mg (30 pills)Chemical Substance: Anastrozole
Anastrozole is a non-steroid drug produced by Balkan Pharmaceuticals Moldova. The trade name “Anastrozole” is also the name of the active substance – Anastrozolum, which is used in this preparation.
Anastrozole is a highly selective inhibitor of aromatase (estrogens) of the third generation.
The form of release – square tablets of yellow color, active substance in 1 tab. 1 mg.
WHY NEED ANASTROZOL IN BODYBUILDING?
Anastrozole can not be substituted for courses of steroids that are highly aromatized (drugs with a high androgenic index.)
As we know the excessive aromatization of steroids, it can lead to the development of a variety of estrogen-dependent side effects:
Development of gynecomastia
A set of body fat in places that are typical for women (buttocks, hips, chest)
The fluid retention in the body, as a result of the effect of “pouring” the muscles, the muscles quickly “clogged” in training.
Increased blood pressure
The drug is taken orally. The tablet is swallowed whole, washed down with water. It is recommended to take the drug at the same time, regardless of food intake.
Adults, including the elderly, are prescribed 1 mg orally 1 time / day for a long time. If signs of disease progression appear, the drug should be discontinued. As an adjuvant therapy, the recommended duration of treatment is 5 years.
If the kidney function is not corrected, dose adjustment is not required.
Correction of the dose in patients with mild to moderate liver function impairment is not required.
The frequency of adverse reactions listed below was determined according to the following criteria: very often (≥ 1/10), often (> 1/100, <1/10); Sometimes (> 1/1000, <1/100); Rarely (> 1/10 000, <1/1000); Very rarely (<1/10 000), including individual messages.
From the side of the cardiovascular system: very often – tides of blood to the face.
From the musculoskeletal system: very often – arthralgia; Rarely a trigger finger.
On the part of the reproductive system: often – dryness of the mucous membrane of the vagina, vaginal bleeding (mainly during the first weeks after the abolition or replacement of the previous hormone therapy for anastrozole).
Application of Anastrozole
Admission (for men):
To suppress the effects of aromatization, athletes should take from 500 μg to 1 mg of anastrozole per day.
Admission (for women):
Exclusively for medical reasons
Side Effects of Anastrozole
In general, the side effects associated with taking aromatase inhibitors include hot flushes, soreness of the joints, general weakness, rapid fatigue, sudden mood swings, depression, high blood pressure, swelling of the hands / feet, and headaches. It is also possible to reduce the level of bone mineral density, resulting in the development of osteoporosis and the increased risk of fractures. Sometimes there may be problems in the GI tract, as well as nausea and vomiting. Strictly forbidden to use during pregnancy, tk. It is possible to disrupt the development of the fetus. When using drugs of this kind by men to reduce estrogen for a long time can lead to the development of cardiovascular diseases because of containing the positive effect of estrogen on the level of cholesterol. In the course of the research, it was found that when combining steroids that tended to aromatize (for example, testosterone enanthate) along with an aromatase inhibitor, then apparent suppression of HDL cholesterol (high-density lipoproteins, “good” cholesterol) begins to manifest. Since Tamoxifen does not generally have the same negative effect on the amount of cholesterol, it is more popular among men – athletes with a problematic cardiovascular system, rather than aromatase inhibitors.