Manufacturer: RPGPack: 100mg 30 pillsChemical Substance: Aldactone (Spironolactone)
Description of pharmacological action
It is a competitive antagonist of aldosterone. In the distal kidney tubules increases the excretion of sodium and water, reduces – potassium. Lowers blood pressure.
Indications for use
Hyperaldosteronism (primary and idiopathic), diagnosis of hyperaldosteronism, adrenal adrenal gland producing aldosterone; Edematous syndrome with chronic heart failure, liver cirrhosis, nephrotic syndrome, nephropathy of pregnant women; Arterial hypertension, hypokalemia, as an adjuvant for malignant hypertension, hypokalemia, prevention of hypokalemia in patients receiving cardiac glycosides.
Addison’s disease, hyperkalemia, hypercalcemia, hyponatremia, chronic renal failure, anuria, hepatic insufficiency, diabetes mellitus with confirmed or suspected chronic renal failure, diabetic nephropathy, I trimester of pregnancy, metabolic acidosis, menstrual irregularity or breast enlargement, hypersensitivity to spironolactone .
In edematic syndrome – 100-200 mg / day (less often – 300 mg / day) in 2-3 hours (usually in combination with a “loop” and / and thiazide diuretic) daily for 14-21 days. Correction of the dose should be carried out taking into account the values of potassium concentration in the plasma. If necessary, the courses are repeated every 10-14 days. With pronounced hyperaldosteronism and reduced potassium content in plasma – 300 mg / day in 2-3 doses.